Structural Analysis of Prostate Cancer N-Glycans Using Graph-Based Structural Metrics
Kalyanthaya M, Gallegos D, Chow J, Pavletic B, Diaz Fernandez AB, Kilcoyne M, Joshi L, Nguyen DH
bioRxiv (preprint) · 2026 · preprint
Physician–scientist · Lima, Peru
Aurora Britania Diaz Fernandez, MD, MSc
Physician-scientist studying how infection, immunity, and the microbiome shape the brain — from rural high-altitude clinics to NASA's astronaut omics data.
- Among Peru’s most selective
- UNSA Medicine
- Brain Analysis Working Group
- NASA OSDR
- Publications · patent application
- 5 · 1
Research areas
From the clinic to microgravity — where infection, immunity, and the microbiome meet.
Immunology & mucosal immunity
Mucosal immune responses and host–pathogen interactions, with bench experience in ELISA, cell culture, and immune profiling.
Neuroinflammation & neurodegeneration
Immune drivers of neuroinflammation and viral reactivation in Alzheimer’s disease, using astronaut and clinical omics datasets.
Microbiome & host–pathogen interactions
High-resolution microbiome profiling and functional prediction to dissect microbial contributions to systemic disease.
Glycobiology & glycan analysis
Computational analysis of glycan structures, 3D alignment, and similarity visualization to probe immune recognition.
Bioinformatics & computational biology
Reproducible pipelines for NGS, viral genomics, and microbiome analysis across Illumina, Nanopore, and PacBio platforms.
Gut–brain axis & immune signaling
How immune–microbial interactions influence brain function, from clinical settings to isolated operational environments.
Aerospace medicine & astronaut health
Human performance, countermeasures, and omics in microgravity and spaceflight analog environments.
Operational & remote medicine
Clinical decision-making under constraints, built through a high-difficulty rural placement in an isolated, high-altitude setting.
Selected research
All research →
2024–present
VIRALL — viral detection and characterization across sequencing platforms
A workflow for viral detection and characterization that scales across sequencing platforms, applied to viral reactivation studies in Alzheimer’s disease.
- Viral genomics
- NGS
- Alzheimer's disease
2024–2025
MicroSeq16S Upgrade — reproducible microbiome pipeline
Methodological update and optimization of a bioinformatic pipeline for microbiome analysis in patients with systemic autoimmune diseases.
- Microbiome
- Snakemake
- QIIME2
2025–present
Kalamiella piersonii — LPS adaptations in spaceflight
Comparative analysis of lipopolysaccharide (LPS) genes from Earth and International Space Station isolates of Kalamiella piersonii.
- Comparative genomics
- Spaceflight
- LPS
2019–2023
Biomedical soft robotic device for lower-limb rehabilitation
Design of a biomedical soft robotic device for lower-limb mechanical muscle rehabilitation and electrochemical monitoring under reduced-gravity space environments.
- Soft robotics
- Space physiology
- Rehabilitation
Selected publications
All publications →
Potential Design Criterions and Constraints for Lunar Settlements: Considerations for the Next Decade
Dev D, Diaz AB, et al.
IAF Human Spaceflight Symposium · 2025 · conference
Design of Biomedical Soft Robotic Device for Lower Limbs Mechanical Rehabilitation under Reduced-Gravity Space Environments
Ticllacuri V, Castrejon N, Diaz AB, et al.
IEEE URUCON 2021 · 2021 · conference